Preclinical Studies in TMEV

2023

Pol S, Dhanraj R,^F Taher A,^G Crever M,^G Charboneau T,^U Schweser F, Dwyer MG, Zivadinov R. Effect of siponimod on brain and spinal cord imaging markers of neurodegeneration in the Theiler’s Murine Encephalomyelitis Virus model of demyelination. Int J Mol Sci 2023;24(16):12990. [Open Article]

Zivadinov R, Schweser F, Dwyer MG, Pol S. Detection of Monocyte/Macrophage and Microglia Activation in the TMEV Model of Chronic Demyelination Using USPIO-Enhanced Ultrahigh-Field Imaging. J Neuroimaging 2020.[Open article]
Pol S, Dhanraj R, Zivadinov R (2020) Bruton tyrosine kinase inhibitor suppresses disease progression in Thieler’s Murine Enchephalomyelitis Virus mouse model of multiple sclerosis. 8th Joint ACTRIMS-ECTRIMS Meeting MS Virtual 2020 September 11-13:P0302.
Zivadinov R, Schweser F, Dwyer M, Pol S (2020) Effect of anti-muCD52 antibody on brain and spinal cord imaging markers of neurodegeneration, microglia, and macrophage activation in the Theiler’s Murine Encephalomyelitis Virus model of chronic demyelination. 72nd Annual Meeting of the American Academy of Neurology, Toronto, Canada April 29:P2:013 [Open article]

Pol S, Sveinsson M, Sudyn M, Babek N, Siebert D, Bertolino N, Modica CM, Preda M, Schweser F and Zivadinov R (2019). "Teriflunomide's Effect on Glia in Experimental Demyelinating Disease: A Neuroimaging and Histologic Study." J Neuroimaging 29(1): 52-61. [Open article]

Modica CM, Schweser F, Sudyn ML, Bertolino N, Preda M, Polak P, Siebert DM, Krawiecki JC, Sveinsson M, Hagemeier J, Dwyer MG, Pol S and Zivadinov R (2017). "Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis." PLoS One 12(8): e0182729. [Open article]

Modica C, Sudyn M, Zivadinov R, Pawlowski D (2016) Shedding risk with intracerebral inoculation of Theiler’s Murine Encephalomyelitis Virus: Informing a risk assessment. Appl Biosaf 2:142-150 [Open article]