The Buffalo Neuroimaging Analysis Center (BNAC) provides comprehensive preclinical core lab services including overall leadership, project management, housing and induction of preclinical models, behavioral testing, creation and execution of image acquisition and analysis protocols, immunology and histology examinations and quality control.

At BNAC, we have the preclinical team, the technology, and the therapeutic expertise to manage your entire medical preclinical trial. Our team, led by BNAC’s Preclinical Director, Dr. Suyog Pol, includes qualified personnel encompassing basic scientists, veterinarians, neuroimagers, and immunology and histology experts with decades of experience in neurology-related therapeutic areas and investigative imaging modalities. In addition, we partner closely with the Center for Biomedical Imaging, a comprehensive core imaging facility at the University at Buffalo (UB) at the Clinical and Translational Science Institute (CTSI). Dr. Robert Zivadinov, the BNAC Director, also serves as the Director of the Center of Biomedical Imaging. 

BNAC’s preclinical expertise includes investigation of the full spectrum of brain, spinal cord and optic nerve disease processes with the following modalities:

  • MRI at 9.4T including cryoprobe
  • Nuclear imaging including various PET tracers
  • 9.4T MRI-PET combined acquisition
  • Contrast MRI sequences for lesion detection
  • Volumetric MRI
  • Axonal imaging
  • Myelin imaging
  • Diffusion tractography
  • Functional MRI and connectomics
  • Magnetic resonance spectroscopy
  • Quantitative susceptibility mapping
  • MRI & MRA including MR perfusion
  • Fluorescent and confocal laser scanning microscopy
  • Immunology examinations

 

Preclinical Models

BNAC has extensive experience with a number of preclinical models in multiple sclerosis and other neurological disorders, as well as post-mortem imaging

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Preclinical Trial Services

We provide a number of preclinical services including housing and induction of the preclinical models, behavioral testing, creation of image acquisition and analysis protocols, immunology and histology examinations

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Preclinical Imaging Endpoints

Our team has expertise in numerous endpoints that can be vital to demonstrate the efficacy of treatments and interventions in preclinical models

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Quality Management System

BNAC is firmly committed to quality and compliance at all stages, including adherence to AAALAC, OLAW, USDA, IACUC, ISO guidelines and certifications

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